Scientists synthesize inorganic-organic hybrid compound that can inhibit breast, lung, liver cancer cells

The solid compound is based on phosphomolybdate cluster, an inorganic salt of phosphomolybdic acid.
Sudha

Updated: Jun 30, 2020 07:26:06 pm

Scientists synthesize inorganic-organic hybrid compound that can inhibit breast, lung, liver cancer cells

30 June 2020 Current Affairs:Scientists from the Institute of Nano Science & Technology (INST), Mohali, have synthesized a novel inorganic-organic hybrid compound that can inhibit breast, lung, and liver cancer cells. It is expected that this will open up new possibilities for metallodrugs.

Highlights:
♦ The solid compound is based on phosphomolybdate cluster, an inorganic salt of phosphomolybdic acid. The compound belongs to the Polyoxometalates (POMs) family, which had earlier been identified to have antitumor potential. 
♦ Scientists have recently figured out the mechanism by which the compound kills the cancer cells. 
♦ POMs are an evolving class of inorganic metal oxides.
♦ The scientists ♦ probed into the mechanism of how the cancer cells are attacked by the compound, the team synthesized it by hydrothermal method.
♦ The results showed that the hybrid solid is less toxic towards normal cells, and its antitumor activity was also found to be comparable with that of a routinely used chemotherapeutic agent.
So far, POMs have evolved as a promising candidate for future metallodrugs for combating cancer.
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