December 2016 Current Affairs
9 DEC
NEWS
8 DEC
NEWS
7 DEC
NEWS
6 DEC
NEWS
5 DEC
NEWS
3 DEC
NEWS

November 2016 Current Affairs
30 NOV
NEWS
29 NOV
NEWS
28 NOV
NEWS
26 NOV
NEWS
25 NOV
NEWS
24 NOV
NEWS

October 2016 Current Affairs
31 OCT
NEWS
27 OCT
NEWS
26 OCT
NEWS
25 OCT
NEWS
24 OCT
NEWS
22 OCT
NEWS

September 2016 Current Affairs
30 SEP
NEWS
29 SEP
NEWS
28 SEP
NEWS
27 SEP
NEWS
26 SEP
NEWS
24 SEP
NEWS

August 2016 Current Affairs
31 AUG
NEWS
30 AUG
NEWS
29 AUG
NEWS
27 AUG
NEWS
26 AUG
NEWS
25 AUG
NEWS

Malaria Vaccine PfSPZ study results show protection for more than 1 year : Researchers

Malaria Vaccine PfSPZ study results show protection for more than 1 year : Researchers
11 May 2016 Current Affairs: In a study conducted on the Malaria vaccine Plasmodium falciparum (Pf) sporozoite (SPZ) [PfSPZ vaccine] to test whether it offers a durable protection against the disease, it was found that the vaccine offered protection for more than 1 year.The study was published in the journal Nature Medicine on 9 May 2016.

The findings of the study suggested that the PfSPZ Vaccine conferred durable protection to malaria through long-lived tissue-resident T cells and that administration of higher doses may further enhance protection

The study was conducted by researchers at National Institute of Allergy and Infectious Diseases (NIAID), part of the US National Institutes of Health and collaborators at the University Of Maryland School Of Medicine in Baltimore.The researchers assessed how vaccine dosage, regimen, and route of administration affected durable protection in malaria-naive adults.

Study : After four intravenous immunizations with 2.7 × 105 PfSPZ, 55% non-parasitemic vaccinated subjects remained without parasitemia following controlled human malaria infection (CHMI) 21 weeks after immunization.45% non-parasitemic subjects from this dosage group underwent repeat CHMI at 59 weeks, and none developed parasitemia.Although Pf-specific serum antibody levels correlated with protection up to 21–25 weeks after immunization, antibody levels waned substantially by 59 weeks. Pf-specific T cell responses also declined in blood by 59 weeks.To determine whether T cell responses in blood reflected responses in liver, researchers vaccinated nonhuman primates with PfSPZ Vaccine and found that Pf-specific interferon-g-producing CD8 T cells were present at ~100-fold higher frequencies in liver than in blood.The result is significant because previous research showed the PfSPZ Vaccine to be highly protective three weeks after immunisation.

PfSPZ vaccine : The vaccine was developed and produced by US-based pharmaceutical company Sanaria in 2013. It contains thousands of live, but weakened P. falciparum sporozoites, which is the early developmental form of the parasite.

 


December 2016 Current affairs
9 DEC
NEWS
8 DEC
NEWS
7 DEC
NEWS
6 DEC
NEWS
5 DEC
NEWS
3 DEC
NEWS

November 2016 Current affairs
30 NOV
NEWS
29 NOV
NEWS
28 NOV
NEWS
26 NOV
NEWS
25 NOV
NEWS
24 NOV
NEWS




October 2016 Current affairs
31 OCT
NEWS
27 OCT
NEWS
26 OCT
NEWS
25 OCT
NEWS
24 OCT
NEWS
22 OCT
NEWS

September 2016 Current affairs
30 SEP
NEWS
29 SEP
NEWS
28 SEP
NEWS
27 SEP
NEWS
26 SEP
NEWS
24 SEP
NEWS

August 2016 Current affairs
31 AUG
NEWS
30 AUG
NEWS
29 AUG
NEWS
27 AUG
NEWS
26 AUG
NEWS
25 AUG
NEWS



FreshersLive - No.1 Job site in India. Fresherslive Current Affairs 2016 section offers informative quiz questions with answers regarding latest current affairs today for all sorts of competitive exams like UPSC, TNPSC , IFS, IAS, IPS, railway exams (RRB) and banking exams like IPBS PO, IPBS clerk, Federal Bank PO, ICICI, SBI, RBI legal officer & Grade officer posts and much more. Register with us to get latest Current Affairs Updates. Also get latest Current Affairs news and quiz Updates for free alerts daily through E-mail

Get Daily Current Affairs to your Email

You can Unsubscribe us at any time.

Get Daily Current Affairs to your Email

You can Unsubscribe us at any time.